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Community Advisory Boards Forum

The Community Advisory Board in Lima

What do you think is important of the iPrEx study?
The CAB thinks that the iPrEx study is important because:

1. It will contribute to find an alternative preventive solution to face HIV infection.
2. iPrEx is an alternative solid scientific proposal in the context of situations that put vulnerable populations at risk.
3. Shall the study be effective, it will be a prevention alternative to HIV infection.
4. If the study probes to be efficacious to prevent HIV infection, it will be an effective solution since the active medication used in iPrEx could have few adverse events, would be tolerable and would generate less resistance.

What do you think of the participation of Peru in iPrEx?
We think that it is positive that Peru is the country where enrollment is a success, since the expected aim has overcome the expectations of the investigators of the study. We are sure shall outcomes are favorable, our country would be one of the direct beneficiaries.

What do you think about iPrEx expansion?
The expansion is important because it will allow the investigation to broad, and with a larger number of participants will allow to answer specific scientific questions that have not been solved yet.

From this perspective it is fundamental to consider the following:

1. One of the main strategies for the iPrEx expansion is prevention counseling to be considered in the study
2. Participants should understand that the study medication—Truvada®—has not been proved to protect against exposure and/or sexual risk behaviors

FIOCRUZ Community Advisory Board (CAB)

Rio de Janeiro Community Advisory Board - CAB -, (CCA in Brazil) was organized in 2002. Our mission is to monitor the development of the research protocols and assure that human rights, ethical procedures and voluntary participation is guaranteed for all participants during every step of protocol implementation, as well as the benefits of the study, in addition to provide community education on prevention and treatment of HIV/AIDS. The CAB acts independently from the clinical trial site team at IPEC/ FIOCRUZ and Hospital Geral de Nova Iguaçu. Our members are volunteers and have the autonomy to define their by laws, operating procedures, and changes in its organization. Nowadays we have seven CAB members meeting every 2 or 3 months on average with flexibility for extra meetings if necessary. The themes for meetings include: a) annual planning, b) protocol specifications, clinical and scientific information; ethical issues; c) information from conference calls and annual meetings. We also organize regularly trainings to the community, and community leaders about research studies, prevention and health promotion emphasizing AIDS epidemic and correlated topics.